Breast cancer chemosensitivity
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Author
Contributions
- Yu, Dihua. - Contributor
- Hung, Mien-chie. - Contributor
Publication
2007 - Landes Bioscience, New York, New York (State)
Language
English
Word Count
43,750 words, Guess
Page Count
175 pages
Identifiers
- Internet Archivebreastcancerchem00yudi
- Internet Archivebreastcancerchem0608unse
- Internet Archivebreastcancerchem00dihu
- ISBN-100387740376
- ISBN-139780387740379
and 4 more
- Library of Congress Control Number2007030520
- OCLC Control Number157002739
- Better World Books9780387740379
- Open LibraryOL14762811M
Classifications
- DDC616.99/449061
- LCCRC280.B8 B6658 2007
- LCCRC254-282
Description
A group of world leading experts review critical aspects of resistance to systemic therapy in breast cancer patients. Beginning with a clinical overview of the problem Chemosensitivity moves on to focus on the latest findings of molecular mechanisms of drug resistance. These include in-depth discussions on multidrug resistance by P-glycoprotein and the multidrug resistance protein family, resistance to therapeutic agent-induced apoptosis, cell cycle deregulation, deregulation of DNA repair, loss of tumor suppressor genes, integrin-mediated adhesion, insulin-like growth factors, epidermal growth factor, and ErbB2 in modulating breast cancer response to systemic therapy, especially, certain chemotherapeutic agents. An example of using novel approaches for chemosensitization of breast cancer cells that gives readers an idea about the future direction in breast cancer treatment.
Subjects
Topics
Other Editions
- Breast cancer chemosensitivity
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