Immunobiology of bacterial CpG-DNA
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Author
Contributions
- Wagner, H. 1941- - Contributor
Publication
2000 - Springer, Berlin
Language
English
Word Count
65,000 words, Guess
Page Count
260 pages
Identifiers
- Open LibraryOL18139118M
- ISBN-103540664009
- OCLC Control Number43266915
- OCLC Control Numberimmunobiologyofb0247unse
- Goodreads3376378
Classifications
- LCCQR185.5 .I46 2000
Description
Bacterial CpG-DNA sequences not only serve for genetic information but act as "danger" signal to alert immune cells such as macrophages & dendritic cells. CpG-DNA directly causes activation of these members of the innate immune system yielding in up-regulation of co-stimulatory molecules & pro-inflammatory cytokines. As such they act as "natural" adjuvants to promote protective Th1 polarized T cell immune responses. This book is the first comprehensive review of the data emerging in this field.
Subjects
Series Statement
- Current topics in microbiology and immunology -- 247.
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