The Philadelphia chromosome
a mutant gene and the quest to cure cancer at the genetic level
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Author
Contributions
- Weinberg, Robert A. (Robert Allan), 1942- - Contributor
Publication
2013 - The Experiment, LLC, New York, New York (State)
Language
English
Word Count
75,750 words, Guess
Page Count
303 pages
Identifiers
- Open LibraryOL27150263M
- ISBN-139781615190676
- ISBN-101615190678
- OCLC Control Number820450840
- OCLC Control Numberphiladelphiachro0000wapn
and 1 more
- Library of Congress Control Number2012047686
Classifications
- DDC616.99/419042
- LCCRC643 .W36 2013
Description
This work discusses the history of a genetic mutation, discovered in 1959, that causes chronic myeloid leukemia, and traces the research and breakthroughs that led to the creation of a drug that makes this once-fatal illness now treatable. It focuses on what is widely viewed as the 'poster child' of rational drug development in the cancer research world. The history of the founding of a genetic mutant chromosome in the indication of Chronic myeloid leukemia disease, and the subsequent development of "Gleevec," is the keynote of this publication.
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- The Philadelphia chromosome: a mutant gene and the quest to cure cancer at the genetic level
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