Contributions

  • David L. DeMets (Editor) - Contributor
  • Curt D. Furberg (Editor) - Contributor
  • Lawrence M. Friedman (Editor) - Contributor

Publication

2005-09-30 - Springer

Language

English

Word Count

93,500 words, Guess

Page Count

374 pages

Identifiers

and 2 more
  • Library of Congress Control Number2005296774
  • Goodreads817797

Classifications

  • LCCR853.C55 D455 2006

Description

This book will be useful to anyone serving on a data and safety monitoring board, or planning to do so, for colleagues in academia, industry and governmental agencies, and for teaching students in biostatistics, epidemiology, clinical trials and medical ethics. It has an extensive collection of cases which provide insight into the many issues, often conflicting, that must be examined before recommendations to continue or discontinue a trial can be made. While depth in statistical methods is not required, some familiarity with statistical design and analysis issues in clinical trials is helpful. The cases cover trials which were terminated early for convincing evidence of benefit, or for harmful effects. Cases with complex issues are also included.

Subjects

Other Editions

  • Data Monitoring in Clinical Trials: A Case Studies ApproachSpringer2005-09-30

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