Genomic disorders
the genomic basis of disease
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Author
Contributions
- Lupski, James R., 1957- - Contributor
- Stankiewicz, Paweł. - Contributor
Publication
2006 - Humana Press, Totowa, N.J, New Jersey
Language
English
Word Count
111,000 words, Guess
Page Count
444 pages
Identifiers
- Open LibraryOL3404982M
- ISBN-101588295591
- OCLC Control Number61121118
- OCLC Control Numbergenomicdisorders00lups_371
- Library of Congress Control Number2005020461
and 1 more
- Goodreads4028053
Classifications
- DDC616/.042
- LCCRB155.5 .G465 2006
Description
A summary and synthesis of the tremendous amount of data now available in the post genomic era on the structural features, architecture, and evolution of the human genome. The authors demonstrate how such architectural features may be important to both evolution and to explaining the susceptibility to those DNA rearrangements associated with disease. Technologies to assay for such structural variation of the human genome and to model genomic disorders in mice are also presented. Two appendices detail the genomic disorders, providing genomic features at the locus undergoing rearrangement, their clinical features, and frequency of detection.
Subjects
Topics
Other Editions
- Genomic disorders: the genomic basis of disease
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