The effects of aging on adult hippocampal neurogenesis in rats.
Our rough guess is there are 36,500 words in this book.
At a pace averaging 250 words per minute, this book will take 2 hours and 26 minutes to read. With a half hour per day, this will take 5 days to read.
How long will it take you?
This book will take an estimated to read at a reading speed averaging words per minute. With 30 minutes per day, this will take to read.
Enter your reading speedYou can take one of our WPM reading speed tests to find your reading speed.
Create a free account to track your reading progress, build your reading list, and set reading goals.
Word Count
36,500 words, Guess
Page Count
146 pages
Identifiers
- ISBN-100612955672
- ISBN-139780612955677
- Open LibraryOL19512906M
Description
This study investigated age-related changes in hippocampal neurogenesis, as well as possible associations between new hippocampal cells and learning and memory impairment during aging. 38-day and 12-month old, male Sprague-Dawley rats were injected with 5-bromo-2'-deoxyuridine (BrdU) in order to label cells dividing in the dentate gyrus, and to follow their fates. Examined at eight time points following injection, aging rats showed a 90% decrease in proliferating cells, but similar proportions of surviving, differentiating, and maturing neurons relative to young. These results indicate that hippocampal neurogenesis, although it occurs on a drastically reduced scale relative to young levels, continues to proceed normally in aging rats. Further, spatial learning following the birth of new granule cells did not appear to directly affect or correlate with cell survival in aging rats. Decreased proliferation will not inevitably lead to deficits in learning, but the new hippocampal cells may be important for long-term memory formation.
Subjects
Links
Reader Reviews
No reviews yet for this book.
Be the first to share your thoughts!